This conference will be a seminal event in advancing the understanding and treatment of Alzheimer’s disease (AD), particularly by bridging the fields of Down Syndrome Alzheimer’s disease (DSAD) and Autosomal Dominant Alzheimer’s disease (ADAD). It emphasizes collaboration, ethical considerations, and inclusivity, fostering a unified approach to tackling both conditions.

A key focus of the conference will be creating lasting networks and collaborations, ensuring that the dialogue and progress continue well beyond the event itself. Building on the success of the previous conference, which attracted close to 200 in-person attendees and many more online from over 20 countries, this second conference aims to expand on that momentum. In addition to the strong support from the DSAD research community, we have renowned international ADAD speakers, with outreach through the DIAN network. The event will promote cross-fertilization of ideas, highlighting the potential for shared insights between these genetically determined forms of AD. This is particularly timely as we now have several ongoing drug development projects in both DSAD and ADAD, with more planned. The exchange of ideas between researchers in these areas is crucial for maximizing the impact of therapeutic strategies.

In conclusion, the conference will cultivate a collaborative, diverse, and inclusive environment to advance research in DSAD and ADAD. The collective expertise of the organizing and scientific committee, combined with support from key stakeholders in Alzheimer’s research, will ensure a successful and impactful event. This gathering represents a significant step forward in global AD research, providing a dynamic platform that fosters connections, innovation, and progress in understanding and treating these intertwined conditions.

Attendees, Inclusivity & Collaboration Strategy to promote Diversity, Equity, and Inclusion:

• Intended Audience: Targeting a diverse group of students, researchers, clinicians, experts, policy-makers, and other stakeholders interested in genetically determined AD.
• Selection Process & Inclusivity: Striving for a balanced and diverse program, selecting top communications from a wide range of contributors.
• Gender Balance & Ethnic and Geographical Diversity: Aiming for balanced representation of gender among speakers, moderators, and attendees. Actively promoting participation from various ethnic backgrounds and geographical regions.
• Early and Senior Researchers: Ensuring a mix of early-career and senior researchers in all sessions.
• Support for Attendees with Families: Provision of daycare services to support those with childcare responsibilities and enable their attendance.